Category: men’s health

Important new research on lymphogranuloma venereum (LGV) in gay men in the UK

Lymphogranuloma venereum (LGV), previously predominantly a tropical disease, re-emerged in Western Europe in 2003, and has arguably now regained endemic status in many countries. It remains largely contained within in a population of men who have sex with men (MSM) with high rates of other sexually transmitted infections (STIs) including HIV, though a first female case was reported in Sexually Transmitted Infections in 2012.

A recent series of papers in Sexually Transmitted Infections sheds further light on the risk factors for rectal LGV in men who have sex with men in the UK, the key symptoms and ways in which LGV presents to the clinician, and pitfalls in the currently recommended treatment and prevention strategies.

Moreover, microbiological  characteristic of LGV repeaters using surveillance data has convinced Rönn and colleagues that behaviour alone does not explain reinfection, which they see as related to centrality in sexual networks.

Together these four articles add important information on the clinical presentation, epidemiology and treatment of LGV in MSM.

Proposed research on why Somalis do not access sexual health services in UK

STIRF had agreed to fund a project by Steve Wordsworh and colleagues from the Faculty of Health, Birmingham City University  investigating the reasons why Somali refugees appear not to access sexual heaalth services. Below is a brief description of the propsed project:

In the United Kingdom there is an established and growing refugee population that have arrived from Somalia. Despite this, the Somali population are often not included in ‘official’ statistics largely because the community is rarely recognised as a distinct ethnic category.

Because of this we often unaware of the health or social needs of those who arrive in the UK from a Somalia background, therefore it is inevitable that the support and needs of this community is often sadly neglected. So despite a very real need for help and support the uptake of health services is very low.

We are particular concerned with low access to sexual health service from of our local Somali community in Birmingham. So building on expertise in both working with the Somali community and in sexual health, staff from BCU are planning to undertake a study that seeks to explore just what exactly are the sexual health needs of Somali refugees, importantly we will be seeking to gather their views and perspectives directly from the community itself, we aim to found out  what they know about sexual health services, the challenges that may prevent them taking up these services and how services could be adapted to best support their needs.

Furthermore, it is our intention that that results from this research can be used to inform service provision by identifying barriers to access and any opportunities that may help to overcome them.

Project on the role of shame in failure to attend for STI and HIV testing shame approved for funding

The 2013 round of applications for funding has resulted in approval for the following pilot project:

Designing a Research project for understanding the role of stigma and shame in STI and HIV testing 

The project will be headed by Phil Hutchinson, Ph.D. (Man.), M.A. (Man.), B.A. (London), Senior Lecturer in Philosophy, Manchester Metropolitan University.

The aim of the preliminary project is to find the methodology to test the hypothesis: is shame one of the reasons for failing  to attend for STI and HIV testing. The project will be completed within six months involving setting up workshops with groups involved with both patient groups and those sexual health care.

HIV testing in the street: a useful tool for widening coverage

The March issue of the journal STI included an article by Sonia Fernandez-Balbuena and colleagues in Madrid which demonstrated that offering HIV testing on the street  may allow a significant number of hard-to reach populations to offer themselves for HIV testing.

Of 7552 persons in various Spanish cities who were asked to full a brief questionnaire and offered HIV testing 3517 participants (47%) were first-time testers. These included 24% of men who have sex with men , 56% of exclusively heterosexual men and 60% of women. 22 undiagnosed HIV infections were detected with a global prevalence of 0.6% and 3.1% in MSM.

The authors concluded that their community programme attracted a substantial number of persons previously untested and particularly hard to reach, such as those with low education and MSM who were least involved in the gay community.

In their view a decisive in decisive factor for almost two of every three persons who had never been tested. was the visibility of the programme.

Sexual behaviour in UK

The National Survey of Sexual Attitudes and lifestyles (Natsal) has been investigating sexual behaviour across a wide range of people, geographical spread and life styles at 10 year intervals since 1990. Natsal is the most extensive, authoritative and accurate investigation of sexual behaviour in the United Kingdom.

The latest report was published as always in the Lancet. The survey shows some interesting changes in sexual behaviour including a narrowing in the gap between men and women in same sex relationships.

Over 15,000 pople were interviewed using validated methodology that minimises bias.  Data were compared between Natsal-1 (1990—91), Natsal-2 (1999—2001), and Natsal-3.

82·1% of men and 77·7%  of women reported at least one sexual partner of the opposite sex in the past year. The proportion generally decreased with age, as did the range of sexual practices with partners of the opposite sex, especially in women.

The increased sexual activity and diversity reported in Natsal-2 in individuals aged 16—44 years when compared with Natsal-1 has generally been sustained in Natsal-3, but in men has generally not risen further. However, there was evidence of increased sexual activity and also increase in same sex activity in women.

In women the number of male sexual partners over the lifetime , proportion reporting ever having had a sexual experience with genital contact with another woman , and proportion reporting at least one female sexual partner in the past 5 years  increased since the last report in 2000.

Interestingly the reported number of occasions of heterosexual intercourse in the past month had reduced but there was a reported expansion of heterosexual sexual repertoires—particularly in oral and anal sex—over time.

Also of note: while acceptance of same-sex partnerships increased so did  intolerance of non-exclusivity in marriage  in men and women in the latest survey.

The authors concluded that:

“Sexual lifestyles in Britain have changed substantially in the past 60 years, with changes in behaviour seeming greater in women than men. The continuation of sexual activity into later life—albeit reduced in range and frequency—emphasises that attention to sexual health and wellbeing is needed throughout the life course.”

Need and acceptability of human papillomavirus (HPV) vaccination in men

HPV vaccination of young women with the quadrivalent vaccine (HPV4) resulted in a dramatic fall in genital warts and cervical cancer rates. However rolling out a similar vaccination in young men has been hampered by arguments that  male HPV4 vaccination programmes exceed cost-effectiveness thresholds.

Unlike the USA and Australia, European countries do not include men in HPV vaccination programmes, instead focusing on achieving expanded coverage among women to promote herd immunity.

Yet there is  evidence that HPV4 vaccination offers substantial clinical benefits to men and is cost effective among men who have sex with men (MSM). MSM have largely been excluded from mathematical models. A recent study in the journal Sexually Transmitted Infections has shown that HPV related conditions such as anal/genital warts and rectal infections are likely to be profoundly underdiagnosed among MSM in most European cities. The paper concluded that there is an urgent need to improve sexual healthcare tailored to MSM at risk for STIs.

There is also the argument  for a gender-neutral (universal) approach to vaccination.

In the same issue of STI a meta-analysis shows that there are currently a number of obstacles to acceptability of HPV vaccination in  men. They concluded that Public health campaigns should aim to promote positive HPV vaccine attitudes and awareness about HPV risk in men. The paper recommended interventions to promote HPV vaccination for boys and to overcome  obstacles to HPV vaccine acceptability for men.

Trichomonas vaginalis – a neglected STI with major global health implications

Trichomonas vaginalis (TV) is the most prevalent curable sexually transmitted infection (STI) globally. Yet at least 80% of TV infections are asymptomatic, though even asymptomatic infections are a public health concern.

In addition to the risk of transmission to sex partners, TV infection has been associated with as much as a 2.7-fold increase in the risk of HIV acquisition, a 1.3-fold increase in the risk of preterm labour, and a 4.7-fold increase in the risk of pelvic inflammatory disease.

A recent review in the journal Sexually Transmitted Infections (STI) highlights the current knowledge of the global epidemiology of TV infection. These include sex differences in the incidence and prevalence of infection, and the potentially important role of female sex hormones, and the menstrual cycle in mediating TV susceptibility and natural history.

WHO has estimated that over half the 248 million new TV infections each year occur in men. By contrast, 89% of prevalent TV cases are found among women. Biological differences between the sexes contribute to these striking differences between men and women.

There has also been an increased understanding of the mechanisms underlying resistance to metronidazole – the current sole drug available to eradicate the organism.

Recent innovations in detection, including the availability of nucleic acid amplification tests (NAATs), have improved our understanding of the natural history of TV infections. These innovations and our increased understanding of this common sexually transmitted infection should help us combat the global epidemic in TV.